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1

Biochemical characterization and mutational studies of a chalcone synthase from yellow snapdragon (Antirrhinum majus) flowers

Hatayama, Masayoshi, Ono, Eiichiro, Yonekura-Sakakibara, Keiko, Tanaka, Yoshikazu, Nishino, Tokuzo, Nakayama, Toru

Journal:

Plant Biotechnology

Year:

2006

File:

PDF, 248 KB

2006

2

Usefulness of Prenyltransferase for Organic Synthesis: Carbon—Carbon Bond Forming Reactions by Prenyltransferases and Their Mutated Enzymes

Yuji Maki, Masahiko Nagaki, Tokuzo Nishino, Tanetoshi Koyama

Journal:

Year:

2002

File:

PDF, 26 KB

2002

3

Cold-active esterase from Psychrobacter sp. Ant300: gene cloning, characterization, and the effects of Gly→Pro substitution near the active site on its catalytic activity and stability

Ljudmila Kulakova, Andrey Galkin, Toru Nakayama, Tokuzo Nishino, Nobuyoshi Esaki

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2004

Language:

english

File:

PDF, 333 KB

english, 2004

4

Amperometric detection of the bacterial metabolic regulation with a microbial array chip

Kuniaki Nagamine, Nobuto Matsui, Takatoshi Kaya, Tomoyuki Yasukawa, Hitoshi Shiku, Toru Nakayama, Tokuzo Nishino, Tomokazu Matsue

Journal:

Biosensors and Bioelectronics

Year:

2005

Language:

english

File:

PDF, 242 KB

english, 2005

5

Polymerase chain reaction-denaturing gradient gel electrophoresis analysis of microbial community structure in landfill leachate

Miho Uchida, Haruna Hatayoshi, Aoi Syuku-nobe, Takefumi Shimoyama, Toru Nakayama, Akitsugu Okuwaki, Tokuzo Nishino, Hisashi Hemmi

Journal:

Journal of Hazardous Materials

Year:

2009

Language:

english

File:

PDF, 446 KB

english, 2009

6

Two isopentenyl pyrophosphate isomerases from pumpkin fruit

Kyozo Ogura, Tokuzo Nishino, Tanetoshi Koyama, Shuichi Seto

Journal:

Year:

1971

Language:

english

File:

PDF, 164 KB

english, 1971

7

Isolation of ergosta-5,7-diene-3β,23ξ-diol from yeast

Shingo Hata, Tokuzo Nishino, Yoshihisa Oda, Hirohiko Katsuki, Yuri Aoyama, Yuzo Yoshida

Journal:

Tetrahedron Letters

Year:

1983

Language:

english

File:

PDF, 117 KB

english, 1983

8

Artificial substrates of medium-chain elongating enzymes, hexaprenyl- and heptaprenyl diphosphate synthases

Masahiko Nagaki, Kosei Kimura, Hiroaki Kimura, Yuji Maki, Eiji Goto, Tokuzo Nishino, Tanetoshi Koyama

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 104 KB

english, 2001

9

Substrate specificity of thermostable farnesyl diphosphate synthase with alkyl group homologs of isopentenyl diphosphate

Masahiko Nagaki, Hiroki Kannari, Junji Ishibashi, Yuji Maki, Tokuzo Nishino, Kyozo Ogura, Tanetoshi Koyama

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1998

Language:

english

File:

PDF, 381 KB

english, 1998

10

Isolation and expression of Paracoccus denitrificans decaprenyl diphosphate synthase gene for production of ubiquinone-10 in Escherichia coli

Seiji Takahashi, Tokuzo Nishino, Tanetoshi Koyama

Journal:

Biochemical Engineering Journal

Year:

2003

Language:

english

File:

PDF, 465 KB

english, 2003

11

An alternative mechanism of product chain-length determination in type III geranylgeranyl diphosphate synthase

Hisashi Hemmi, Motoyoshi Noike, Toru Nakayama, Tokuzo Nishino

Journal:

Year:

2003

Language:

english

File:

PDF, 367 KB

english, 2003

12

Mechanism of product chain length determination for heptaprenyl diphosphate synthase from Bacillus stearothermophilus

Kazutake Hirooka, Shin-ichi Ohnuma, Ayumi Koike-Takeshita, Tanetoshi Koyama, Tokuzo Nishino

Journal:

Year:

2000

Language:

english

File:

PDF, 780 KB

english, 2000

13

cDNA cloning of a BAHD acyltransferase from soybean (Glycine max): Isoflavone 7-O-glucoside-6″-O-malonyltransferase

Hirokazu Suzuki, Tokuzo Nishino, Toru Nakayama

Journal:

Year:

2007

Language:

english

File:

PDF, 461 KB

english, 2007

14

Identification and characterization of a novel anthocyanin malonyltransferase from scarlet sage (Salvia splendens) flowers: an enzyme that is phylogenetically separated from other anthocyanin acyltransferases

Hirokazu Suzuki, Shin'ya Sawada, Kazufumi Watanabe, Shiro Nagae, Masa-atsu Yamaguchi, Toru Nakayama, Tokuzo Nishino

Journal:

The Plant Journal

Year:

2004

Language:

english

File:

PDF, 317 KB

english, 2004

15

Localization of a flavonoid biosynthetic polyphenol oxidase in vacuoles

Eiichiro Ono, Masayoshi Hatayama, Yuri Isono, Takuya Sato, Ryoko Watanabe, Keiko Yonekura-Sakakibara, Masako Fukuchi-Mizutani, Yoshikazu Tanaka, Takaaki Kusumi, Tokuzo Nishino, Toru Nakayama

Journal:

The Plant Journal

Year:

2006

Language:

english

File:

PDF, 821 KB

english, 2006

16

Type 2 isopentenyl diphosphate isomerase from a thermoacidophilic archaeon Sulfolobus shibatae

Satoshi Yamashita, Hisashi Hemmi, Yosuke Ikeda, Toru Nakayama, Tokuzo Nishino

Journal:

Year:

2004

Language:

english

File:

PDF, 311 KB

english, 2004

17

Geranylgeranyl reductase involved in the biosynthesis of archaeal membrane lipids in the hyperthermophilic archaeon Archaeoglobus fulgidus

Motomichi Murakami, Kyohei Shibuya, Toru Nakayama, Tokuzo Nishino, Tohru Yoshimura, Hisashi Hemmi

Journal:

Year:

2007

Language:

english

File:

PDF, 653 KB

english, 2007

18

The product chain length determination mechanism of type II geranylgeranyl diphosphate synthase requires subunit interaction

Motoyoshi Noike, Takashi Katagiri, Toru Nakayama, Tanetoshi Koyama, Tokuzo Nishino, Hisashi Hemmi

Journal:

Year:

2008

Language:

english

File:

PDF, 733 KB

english, 2008

19

A thermophilic cyanobacterium Synechococcus elongatus has three different Class I prenyltransferase genes

Chikara Ohto, Chika Ishida, Hiroyuki Nakane, Masayoshi Muramatsu, Tokuzo Nishino, Shusei Obata

Journal:

Plant Molecular Biology

Year:

1999

Language:

english

File:

PDF, 423 KB

english, 1999

20

Effect of mutagenesis at the region upstream from the G(Q/E) motif of three types of geranylgeranyl diphosphate synthase on product chain-length

Motoyoshi Noike, Takashi Katagiri, Toru Nakayama, Tokuzo Nishino, Hisashi Hemmi

Journal:

Journal of Bioscience and Bioengineering

Year:

2009

Language:

english

File:

PDF, 674 KB

english, 2009

21

Production of tetraketide lactones by mutated Antirrhinum majus chalcone synthases (AmCHS1)

Masayoshi Hatayama, Hideaki Unno, Masami Kusunoki, Seiji Takahashi, Tokuzo Nishino, Toru Nakayama

Journal:

Journal of Bioscience and Bioengineering

Year:

2010

Language:

english

File:

PDF, 868 KB

english, 2010

22

cDNA cloning and functional characterization of flavonol 3-O-glucoside-6″-O-malonyltransferases from flowers of Verbena hybrida and Lamium purpureum

Hirokazu Suzuki, Toru Nakayama, Shiro Nagae, Masa-Atsu Yamaguchi, Takashi Iwashita, Yuko Fukui, Tokuzo Nishino

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2004

Language:

english

File:

PDF, 470 KB

english, 2004

23

cDNA cloning of glycosyltransferases from Chinese wolfberry (Lycium barbarum L.) fruits and enzymatic synthesis of a catechin glucoside using a recombinant enzyme (UGT73A10)

Akio Noguchi, Nobuhiro Sasaki, Masahiro Nakao, Harukazu Fukami, Seiji Takahashi, Tokuzo Nishino, Toru Nakayama

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2008

Language:

english

File:

PDF, 457 KB

english, 2008

24

Kinetic and thermodynamic characterization of the cold activity acquired upon single amino-acid substitution near the active site of a thermostable α-glucosidase

Akio Noguchi, Tokuzo Nishino, Toru Nakayama

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2009

Language:

english

File:

PDF, 354 KB

english, 2009

25

Unique primary structure of a thermostable multimetal β-galactosidase from Saccharopolyspora rectivirgula

Misa Inohara-Ochiai, Toru Nakayama, Masahiro Nakao, Tsuyoshi Fujita, Takashi Ueda, Toshihiko Ashikari, Tokuzo Nishino, Yuji Shibano

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1998

Language:

english

File:

PDF, 978 KB

english, 1998

26

One-pot syntheses of the sex pheromone homologs of a codling moth, Laspeyresia promonella L.

Masahiko Nagaki, Akiyuki Takaya, Yuji Maki, Junji Ishibashi, Yoko Kato, Tokuzo Nishino, Tanetoshi Koyama

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2000

Language:

english

File:

PDF, 116 KB

english, 2000

27

A cold-active esterase with a substrate preference for vinyl esters from a psychrotroph, Acinetobacter sp. strain no. 6: gene cloning, purification, and characterization

Takeshi Suzuki, Toru Nakayama, Tatsuo Kurihara, Tokuzo Nishino, Nobuyoshi Esaki

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2002

Language:

english

File:

PDF, 143 KB

english, 2002

28

Substrate specificity of thermostable farnesyl diphosphate synthase with respect to 4-alkyl group homologs of isopentenyl diphosphate

Masahiko Nagaki, Hiroto Yamamoto, Ayumi Takahashi, Yuji Maki, Junji Ishibashi, Tokuzo Nishino, Tanetoshi Koyama

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2002

Language:

english

File:

PDF, 100 KB

english, 2002

29

Site-specific mutagenesis at positions 272 and 273 of the Bacillus sp. SAM1606 α-glucosidase to screen mutants with altered specificity for oligosaccharide production by transglucosylation

Maki Okada, Toru Nakayama, Akio Noguchi, Masayasu Yano, Hisashi Hemmi, Tokuzo Nishino, Takashi Ueda

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2002

Language:

english

File:

PDF, 376 KB

english, 2002

30

Substrate specificities of medium-prenylchain elongating enzymes, hexaprenyl- and heptaprenyl diphosphate synthases

Masahiko Nagaki, Kazuhiro Kuwahara, Kosei Kimura, Jun Kawakami, Yuji Maki, Shunji Ito, Noboru Morita, Tokuzo Nishino, Tanetoshi Koyama

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2003

Language:

english

File:

PDF, 102 KB

english, 2003

31

Dramatic changes in the substrate specificities of prenyltransferase by a single amino acid substitution

Yuji Maki, Mariko Komabayashi, Yoshinori Gotoh, Norimasa Ohya, Hisashi Hemmi, Kazutake Hirooka, Tokuzo Nishino, Tanetoshi Koyama

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2002

Language:

english

File:

PDF, 135 KB

english, 2002

32

Improvement of thermostability of cold-active serine alkaline protease from the psychrotrophic bacterium Shewanella sp. strain Ac10 by rational mutagenesis

Ljudmila Kulakova, Andrey Galkin, Toru Nakayama, Tokuzo Nishino, Nobuyoshi Esaki

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2003

Language:

english

File:

PDF, 191 KB

english, 2003

33

Anthocyanin acyltransferases: specificities, mechanism, phylogenetics, and applications

Toru Nakayama, Hirokazu Suzuki, Tokuzo Nishino

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2003

Language:

english

File:

PDF, 341 KB

english, 2003

34

Artificial substrates for undecaprenyl diphosphate synthase from Micrococcus luteus B-P 26

Masahiko Nagaki, Shunsuke Sato, Yuji Maki, Tokuzo Nishino, Tanetoshi Koyama

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2000

Language:

english

File:

PDF, 99 KB

english, 2000

35

Thermostable collagenolytic activity of a novel thermophilic isolate, Bacillus sp. strain NTAP-1

Toru Nakayama, Naoki Tsuruoka, Minoru Akai, Tokuzo Nishino

Journal:

Journal of Bioscience and Bioengineering

Year:

2000

Language:

english

File:

PDF, 332 KB

english, 2000

36

An active-site mutation causes enhanced reactivity and altered regiospecificity of transglucosylation catalyzed by the Bacillus sp. SAM1606 α-glucosidase

Misa Inohara-Ochiai, Maki Okada, Toru Nakayama, Hisashi Hemmi, Takashi Ueda, Takashi Iwashita, Yukiko Kan, Yuji Shibano, Toshihiko Ashikari, Tokuzo Nishino

Journal:

Journal of Bioscience and Bioengineering

Year:

2000

Language:

english

File:

PDF, 871 KB

english, 2000

37

Mutational analysis of the role of His452 of Saccharopolyspora rectivirgula β-galactosidase

Toru Nakayama, Yuka Goto, Satoshi Hasegawa, Misa Inohara-Ochiai, Yuji Shibano, Toshihiko Ashikari, Tokuzo Nishino

Journal:

Journal of Bioscience and Bioengineering

Year:

2000

Language:

english

File:

PDF, 606 KB

english, 2000

38

Cold-active lipolytic activity of psychrotrophic Acinetobacter sp. strain no. 6

Takeshi Suzuki, Toru Nakayama, Tatsuo Kurihara, Tokuzo Nishino, Nobuyoshi Esaki

Journal:

Journal of Bioscience and Bioengineering

Year:

2001

Language:

english

File:

PDF, 632 KB

english, 2001

39

Novel sugar phosphotransferase system applicable to the efficient labeling of the compounds synthesized via the non-mevalonate pathway in Escherichia coli

Hisashi Hemmi, Satoshi Yamashita, Toru Nakayama, Tokuzo Nishino

Journal:

Journal of Bioscience and Bioengineering

Year:

2002

Language:

english

File:

PDF, 472 KB

english, 2002

40

Introduction of the archaebacterial geranylgeranyl pyrophosphate synthase gene into Chlamydomonas reinhardtii chloroplast

Ei-Ichiro Fukusaki, Takashi Nishikawa, Ko Kato, Atsuhiko Shinmyo, Hisashi Hemmi, Tokuzo Nishino, Akio Kobayashi

Journal:

Journal of Bioscience and Bioengineering

Year:

2003

Language:

english

File:

PDF, 664 KB

english, 2003

41

Deletion and insertion of a 192-residue peptide in the active-site domain of glycosyl hydrolase family-2 β-galactosidases

Misa Inohara-Ochiai, Satoshi Hasegawa, Sota Iguchi, Toshihiko Ashikari, Yuji Shibano, Hisashi Hemmi, Toru Nakayama, Tokuzo Nishino

Journal:

Journal of Bioscience and Bioengineering

Year:

2002

Language:

english

File:

PDF, 1.33 MB

english, 2002

42

Molecular biological analysis of microflora in a garbage treatment process under thermoacidophilic conditions

Hisashi Hemmi, Takefumi Shimoyama, Toru Nakayama, Katsuji Hoshi, Tokuzo Nishino

Journal:

Journal of Bioscience and Bioengineering

Year:

2004

Language:

english

File:

PDF, 1.21 MB

english, 2004

43

Molecular cloning and characterization of a thermostable carboxylesterase from an archaeon, Sulfolobus shibatae DSM5389: Non-linear kinetic behavior of a hormone-sensitive lipase family enzyme

Koki Ejima, Jian Liu, Yasuhiro Oshima, Kazutake Hirooka, Shoko Shimanuki, Yukako Yokota, Hisashi Hemmi, Toru Nakayama, Tokuzo Nishino

Journal:

Journal of Bioscience and Bioengineering

Year:

2004

Language:

english

File:

PDF, 492 KB

english, 2004

44

Microbial diversity in biodegradation and reutilization processes of garbage

Shin Haruta, Toru Nakayama, Kohei Nakamura, Hisashi Hemmi, Masaharu Ishii, Yasuo Igarashi, Tokuzo Nishino

Journal:

Journal of Bioscience and Bioengineering

Year:

2005

Language:

english

File:

PDF, 677 KB

english, 2005

45

Crystallization and Preliminary X-ray Diffraction Studies of Bacillus stearothermophilus Farnesyl Diphosphate Synthase Expressed in Escherichia coli

Hiroyuki Nakane, Tanetoshi Koyama, Shusei Obata, Masami Osabe, Ayumi Takeshita, Tokuzo Nishino, Kyozo Ogura, Kunio Miki

Journal:

Journal of Molecular Biology

Year:

1993

File:

PDF, 115 KB

1993

46

The synthesis of 3-nonaprenyl-4-hydroxybenzoate in rat liver mitochondria: The effect of Ca2+, Mg2+, chelators, and bacitracin on the activity of p-hydroxybenzoate-polyprenyl transferase

Nisson Schechter, Tokuzo Nishino, Harry Rudney

Journal:

Archives of Biochemistry and Biophysics

Year:

1973

Language:

english

File:

PDF, 529 KB

english, 1973

47

Reactivity of artificial substrates for prenyltransferase

Tokuzo Nishino, Kyozo Ogura, Shuchi Seto

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1971

Language:

english

File:

PDF, 205 KB

english, 1971

48

Comparative specificity of prenyltransferase of pig liver and pumpkin with respect to artificial substrates

Tokuzo Nishino, Kyozo Ogura, Shuichi Seto

Journal:

Biochimica et Biophysica Acta (BBA) - Enzymology

Year:

1973

Language:

english

File:

PDF, 288 KB

english, 1973

49

Characterization of sterol-ester synthetase in saccharomyces cerevisiae

Taketani Shigeru, Nishino Tokuzo, Katsuki Hirohiko

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1979

Language:

english

File:

PDF, 539 KB

english, 1979

50

Polyprenyl diphosphate synthase essentially defines the length of the side chain of ubiquinone

Kazunori Okada, Kengo Suzuki, Yasuhiro Kamiya, XuFen Zhu, Shingo Fujisaki, Yukinobu Nishimura, Tokuzo Nishino, Tsuyoshi Nakagawad, Makoto Kawamukai, Hideyuki Matsuda

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Year:

1996

Language:

english

File:

PDF, 666 KB

english, 1996